Functional equivalency and diversity of cis-acting elements among yeast replication origins
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چکیده
منابع مشابه
cis- and trans-acting elements in flavivirus RNA replication.
Most of the seven flavivirus nonstructural proteins (NS1 to NS5) encoded in the distal two-thirds of the RNA positive-sense genome are believed to be essential components of RNA replication complexes. To explore the functional relationships of these components in RNA replication, we used trans-complementation analysis of full-length infectious RNAs of Kunjin (KUN) virus with a range of lethal i...
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INTRODUCTION................................................... 492 The Cast of Characters ................................................... 492 Dispersal of Alphaviruses................................................... 494 Full-Length Clones of Alphaviruses ................................................... 494 STRUCTURE OF ALPHAVIRUSES ................................................... ...
متن کاملThe cis-acting replication elements define human enterovirus and rhinovirus species.
Replication of picornaviruses is dependent on VPg uridylylation, which is linked to the presence of the internal cis-acting replication element (cre). Cre are located within the sequence encoding polyprotein, yet at distinct positions as demonstrated for poliovirus and coxsackievirus-B3, cardiovirus, and human rhinovirus (HRV-A and HRV-B), overlapping proteins 2C, VP2, 2A, and VP1, respectively...
متن کاملGlobal synonymous mutagenesis identifies cis-acting RNA elements that regulate HIV-1 splicing and replication
The ~9.5 kilobase HIV-1 genome contains RNA sequences and structures that control many aspects of viral replication, including transcription, splicing, nuclear export, translation, packaging and reverse transcription. Nonetheless, chemical probing and other approaches suggest that the HIV-1 genome may contain many more RNA secondary structures of unknown importance and function. To determine wh...
متن کاملcis-acting elements in the lytic origin of DNA replication of Epstein-Barr virus.
oriLyt, the cis-acting element of Epstein-Barr virus, mediates viral DNA replication in the lytic phase of the virus's life cycle. Oligonucleotide-directed in vitro mutagenesis of oriLyt plasmids allowed the identification of two noncontiguous components within the complex structure of oriLyt. Both components were indispensable for DNA replication of this origin. The upstream component colocali...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 1997
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.17.9.5473